Intranasal administration of polysulfide prevents neurodegeneration in spinal cord and rescues mice from delayed paraplegia after spinal cord ischemia
Background: Delayed paraplegia is a devastating complication mariya b vol 3 of thoracoabdominal aortic surgery.Hydrogen sulfide (H2S) was reported to be protective in a mouse model of spinal cord ischemia and the beneficial effect of H2S has been attributed to polysulfides.The objective of this study was to investigate the effects of polysulfides o